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 : The "Tightness Factor" (T.F)  measurements for medical clean rooms 
Keeping up the tightness factor dramatically improves the performance of medical clean rooms, improves the filtration process, the humidity and temperature control.
When tightness is poor, every opening of the door, little cracks or holes cause a purge of contaminated air into  the room .
Standard tightness factor is reached in a room where pressure loss rate from 160 Pascal to 60 Pascal  lasts more then 12 seconds . In this case the outside air penetration rate is smaller than  0.5 percent of the room volume in one minute and the filtration recovery system can cope with this amount of contamination and keep the room clean.      

A clean room is a room that maintains a high tightness factor and the rate of filtration is higher than the rate of contamination


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